Mechanism of Aurora-B activation by INCENP and inhibition by Hesperadin.

PDB Details

PDB ID
2BFX
Status
CURRENT
Deposition Date
2004-12-15
Modification Date
2015-05-20
Pubmed ID
15866179
Method
X-RAY DIFFRACTION
Resolution (Å)
1.8
UniProt Accessions
Q6DE08

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 0 21
A C EDI 4 10
A C AAS 5 8
A C CMP 7 6
A N ATP 1 16
A N PIF 2 16
A N PIF 4 9
A N MPP 5 7
A N PIF 7 5
A N MT3 8 3
B C AAS 2 14
B C EDI 3 14
B N ATP 0 16
B N PIF 1 15
B N MPP 2 15
B N PIF 3 14
B N MT3 6 7

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Legend

Color Name Hit Count