CRYSTAL STRUCTURE OF EGFR KINASE DOMAIN T790M MUTATION

PDB Details

PDB ID
2JIT
Status
CURRENT
Deposition Date
2007-07-01
Modification Date
2009-02-24
Pubmed ID
18227510
Method
X-RAY DIFFRACTION
Resolution (Å)
3.1
UniProt Accessions
P00533

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DRS 5 6
A C LBP 6 6
A C PDIG 9 4
A C LBP 11 2
A N MPP 0 25
A N DFG 2 15
A N ATP 3 12
A N MPP 5 6
A N MT3 8 2
B C EDI 4 10
B C ATP 7 4
B N MT3 1 16
B N DFG 4 12
B N MPP 5 10

Mapping Results Viewer

Use your mouse to drag, rotate, and zoom. Select structure to view on the right using dropdown.

Legend

Color Name Hit Count