Crystal structure of EGFR kinase domain T790M mutation in compex with HKI-272

PDB Details

PDB ID
2JIV
Status
CURRENT
Deposition Date
2007-07-02
Modification Date
2015-11-11
Pubmed ID
18227510
Method
X-RAY DIFFRACTION
Resolution (Å)
3.5
UniProt Accessions
P00533

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 3 10
A C CMP 9 2
A N ATP 1 18
A N MT3 2 16
A N MT3 3 14
A N PIF 4 7
A N MPP 6 4
A N MT3 7 4
A N ATP 8 3
B N MT3 0 16
B N ATP 1 16
B N MPP 3 15
B N MT3 4 14
B N MT3 5 9
B N MT3 7 3

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Legend

Color Name Hit Count