Synthesis and SAR of Aminopyrimidines as Novel c-Jun N-Terminal Kinase (JNK) Inhibitors

PDB Details

PDB ID
2P33
Status
CURRENT
Deposition Date
2007-03-08
Modification Date
2009-02-24
Pubmed ID
17459703
Method
X-RAY DIFFRACTION
Resolution (Å)
2.4
UniProt Accessions
P53779

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 0 20
A C DEF 2 16
A C EDI 3 14
A C DRS 4 8
A C DFG 5 5
A C CMP 6 4
A C PDIG 7 4
A N ATP 0 20
A N PIF 1 19
A N MT3 2 14
A N ATP 3 9
A N MT3 6 7

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Legend

Color Name Hit Count