Crystal Strucure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K659N Mutation Responsible for an Unclassified Craniosynostosis Syndrome.

PDB Details

PDB ID
2PVY
Status
CURRENT
Deposition Date
2007-05-10
Modification Date
2012-03-07
Pubmed ID
17803937
Method
X-RAY DIFFRACTION
Resolution (Å)
2.2
UniProt Accessions
P21802

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DEF 3 16
A N PIF 0 19
A N MPP 2 15
A N ATP 3 14
A N ATP 5 9
A N MPP 6 7
A N DFG 7 2
B C CMP 3 12
B C EDI 4 10
B C CMP 6 6
B C DRS 9 2
B N MPP 1 19
B N ATP 3 13
B N MPP 4 8
B N ATP 6 5
C C CMP 1 16
C C CMP 5 5
C C EDI 6 5
C C AAS 8 4
C N MPP 1 16
C N ATP 2 12
C N MPP 4 11
C N ATP 6 10
D C CMP 6 7
D N MPP 0 20
D N PIF 2 17
D N ATP 4 12
D N ATP 5 7

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Legend

Color Name Hit Count