Crystal Strucure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic N549H Mutation Responsible for Crouzon Syndrome.

PDB Details

PDB ID
2PWL
Status
CURRENT
Deposition Date
2007-05-11
Modification Date
2012-02-22
Pubmed ID
17803937
Method
X-RAY DIFFRACTION
Resolution (Å)
2.4
UniProt Accessions
P21802

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 5 12
A C DRS 7 3
A N MPP 0 29
A N ATP 1 18
A N ATP 5 4
B C EDI 4 12
B N ATP 1 18
B N MPP 3 16
B N MPP 4 14
B N ATP 5 5

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Legend

Color Name Hit Count