Crystal Strucure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic E565G Mutation Responsible for Pfeiffer Syndrome

PDB Details

PDB ID
2PY3
Status
CURRENT
Deposition Date
2007-05-15
Modification Date
2012-03-07
Pubmed ID
17803937
Method
X-RAY DIFFRACTION
Resolution (Å)
2.3
UniProt Accessions
P21802

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C LBP 4 9
A C EDI 7 6
A C DRS 8 4
A N PIF 0 21
A N MPP 2 16
A N ATP 3 14
A N MPP 4 10
A N ATP 5 6
A N DFG 7 4
B C EDI 3 13
B N MPP 2 14
B N ATP 4 12
B N MPP 5 10
B N ATP 6 6

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Legend

Color Name Hit Count