Crystal Strucure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic N549T Mutation Responsible for Pfeiffer Syndrome

PDB Details

PDB ID
2PZ5
Status
CURRENT
Deposition Date
2007-05-17
Modification Date
2012-02-22
Pubmed ID
17803937
Method
X-RAY DIFFRACTION
Resolution (Å)
2.4
UniProt Accessions
P21802

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 5 8
A C DRS 7 3
A N PIF 0 17
A N MPP 1 13
A N MPP 2 12
A N ATP 4 12
A N ATP 6 8
A N DFG 9 3
A N DFG 10 1
B C EDI 4 11
B C CMP 5 8
B C CMP 6 5
B N PIF 0 23
B N ATP 1 14
B N ATP 4 12
B N DFG 5 8
B N MPP 6 6
B N MPP 8 2

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Legend

Color Name Hit Count