Crystal Strucure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K526E Mutation Responsible for Crouzon Syndrome

PDB Details

PDB ID
2PZP
Status
CURRENT
Deposition Date
2007-05-18
Modification Date
2012-02-22
Pubmed ID
17803937
Method
X-RAY DIFFRACTION
Resolution (Å)
2.4
UniProt Accessions
P21802

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C LBP 5 7
A C DRS 10 5
A N ATP 0 19
A N PIF 1 18
A N ATP 4 9
A N MPP 5 8
A N DFG 8 5
A N MPP 9 2
A N MPP 10 1
B C EDI 4 11
B C CMP 5 6
B C DRS 7 4
B C LBP 11 2
B N PIF 0 21
B N ATP 2 15
B N MPP 4 9
B N ATP 6 7
B N DFG 7 4

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Legend

Color Name Hit Count