Crystal Strucure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K641R Mutation Responsible for Pfeiffer Syndrome

PDB Details

PDB ID
2PZR
Status
CURRENT
Deposition Date
2007-05-18
Modification Date
2012-03-07
Pubmed ID
17803937
Method
X-RAY DIFFRACTION
Resolution (Å)
3.0
UniProt Accessions
P21802

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 1 12
A C DRS 3 11
A C LBP 7 3
A N PIF 0 19
A N MPP 1 14
A N ATP 4 11
A N DFG 5 10
A N ATP 6 10
B C EDI 4 11
B C LBP 6 4
B N MPP 2 14
B N ATP 4 8
B N DFG 7 4
B N ATP 8 4

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Legend

Color Name Hit Count