IRAK-4 Inhibitors (Part II)- A structure based assessment of imidazo[1,2 a]pyridine binding

PDB Details

PDB ID
3CGF
Status
CURRENT
Deposition Date
2008-03-05
Modification Date
2009-02-24
Pubmed ID
18482836
Method
X-RAY DIFFRACTION
Resolution (Å)
3.0
UniProt Accessions
P53779

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 0 21
A C EDI 1 20
A C DEF 3 13
A C DFG 5 9
A C EDI 6 3
A C DRS 8 2
A N PIF 0 19
A N ATP 1 18
A N MT3 2 16
A N MT3 7 4

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Legend

Color Name Hit Count