IRAK-4 Inhibitors (Part II)- A structure based assessment of imidazo[1,2 a]pyridine binding

PDB Details

PDB ID
3CGO
Status
CURRENT
Deposition Date
2008-03-06
Modification Date
2009-02-24
Pubmed ID
18482836
Method
X-RAY DIFFRACTION
Resolution (Å)
3.0
UniProt Accessions
P53779

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 0 24
A C EDI 1 15
A C DEF 2 14
A C EDI 3 11
A C DRS 4 11
A C CMP 5 6
A C PDIG 8 2
A N ATP 0 18
A N MT3 1 17
A N PIF 2 16
A N ATP 4 7
A N MT3 7 2
A N ATP 8 2

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Legend

Color Name Hit Count