Crystal structure of mouse Aurora A (Asn186->Gly, Lys240->Arg, Met302->Leu) in complex with 1-(3-chloro-phenyl)-3-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)- ethyl]-thiazol-2-yl}-urea [SNS-314]

PDB Details

PDB ID
3D15
Status
CURRENT
Deposition Date
2008-05-04
Modification Date
2013-06-19
Pubmed ID
18678489
Method
X-RAY DIFFRACTION
Resolution (Å)
2.3
UniProt Accessions
P97477

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 0 29
A C AAS 1 25
A C CMP 3 15
A C EDI 4 5
A C AAS 5 3
A C EDI 6 2
A N MPP 0 22
A N MT3 1 21
A N ATP 2 17
A N MT3 3 11
A N PIF 6 8

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Legend

Color Name Hit Count