Crystal Structure of EGFR 696-1022 T790M Mutant Covalently Binding to WZ4002

PDB Details

PDB ID
3IKA
Status
CURRENT
Deposition Date
2009-08-05
Modification Date
2010-01-12
Pubmed ID
20033049
Method
X-RAY DIFFRACTION
Resolution (Å)
2.9
UniProt Accessions
P00533

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DRS 1 15
A C PDIG 5 8
A C LBP 10 2
A C LBP 11 2
A N DFG 0 15
A N ATP 1 15
A N MPP 5 8
A N MPP 8 4
A N MPP 9 3
A N DFG 10 3
B C DRS 2 16
B C ATP 4 12
B C EDI 6 5
B C CMP 7 2
B N MT3 0 24
B N MPP 1 16
B N DFG 2 14
B N ATP 6 4

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Legend

Color Name Hit Count