Crystal structure of bisphosphorylated IGF1-R Kinase domain (2P) in complex with a bis-azaindole inhibitor

PDB Details

PDB ID
3LVP
Status
CURRENT
Deposition Date
2010-02-22
Modification Date
2010-07-21
Pubmed ID
20545947
Method
X-RAY DIFFRACTION
Resolution (Å)
3.0
UniProt Accessions
P08069

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DRS 3 11
A C CMP 5 8
A N MPP 0 19
A N PIF 2 13
A N ATP 3 13
A N MT3 4 11
A N DFG 6 6
A N ATP 8 2
B C DRS 0 26
B C DRS 4 5
B C CMP 6 4
B C DRS 10 2
B N PIF 1 22
B N ATP 4 8
B N DFG 7 2
C C DRS 0 29
C C CMP 5 4
C N MPP 1 17
C N PIF 4 11
C N ATP 5 8
D C DRS 0 29
D C DRS 4 6
D C DRS 8 3
D C DRS 9 2
D N MPP 0 18
D N ATP 3 16
D N DFG 6 4
D N DFG 7 3

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Legend

Color Name Hit Count