Structural and Thermodynamic Characterization of the TYK2 and JAK3 Kinase Domains in Complex with CP-690550 and CMP-6

PDB Details

PDB ID
3LXN
Status
CURRENT
Deposition Date
2010-02-25
Modification Date
2010-07-28
Pubmed ID
20478313
Method
X-RAY DIFFRACTION
Resolution (Å)
2.5
UniProt Accessions
P29597

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C CMP 3 12
A C AAS 9 3
A N DFG 1 15
A N ATP 3 12
A N MT3 5 9

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Legend

Color Name Hit Count