Crystal structure of the ACVR1 kinase in complex with a 2-aminopyridine inhibitor

PDB Details

PDB ID
3MTF
Status
CURRENT
Deposition Date
2010-04-30
Modification Date
2014-06-18
Pubmed ID
23646137
Method
X-RAY DIFFRACTION
Resolution (Å)
2.15
UniProt Accessions
Q04771

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C AAS 0 18
A C EDI 1 14
A C AAS 5 6
A C DRS 8 4
A N DFG 0 22
A N ATP 2 15
A N ATP 3 15
A N ATP 7 2
B C EDI 0 18
B C AAS 1 17
B C AAS 7 4
B N ATP 2 16
B N ATP 3 15
B N DFG 4 14

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Legend

Color Name Hit Count