X-Ray Co-structure of Rho-Associated Protein Kinase (ROCK1) with a potent 2H-isoquinolin-1-one inhibitor

PDB Details

PDB ID
3NCZ
Status
CURRENT
Deposition Date
2010-06-06
Modification Date
2010-12-08
Pubmed ID
20678931
Method
X-RAY DIFFRACTION
Resolution (Å)
3.0
UniProt Accessions
Q13464

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DRS 3 13
A C AAS 4 8
A N ATP 2 14
A N MT3 8 3
B C EDI 0 19
B N ATP 2 14
C C DRS 2 12
C C PDIG 4 10
C C PDIG 5 9
C N ATP 2 15
D C DRS 0 19
D C AAS 2 17
D C AAS 6 6
D C EDI 7 2
D N ATP 1 15

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Legend

Color Name Hit Count