Crystal structure of Rho-Associated Protein Kinase (ROCK1) with a potent isoquinolone derivative

PDB Details

PDB ID
3NDM
Status
CURRENT
Deposition Date
2010-06-07
Modification Date
2011-07-13
Pubmed ID
20471253
Method
X-RAY DIFFRACTION
Resolution (Å)
3.3
UniProt Accessions
Q13464

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DRS 2 15
A C DRS 7 5
A N ATP 1 16
B C DRS 0 19
B N ATP 0 15
C C DRS 3 12
C C PDIG 9 2
C N ATP 3 14
D C DRS 6 7
D C CMP 9 2
D N ATP 1 17

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Legend

Color Name Hit Count