Highly Selective c-Jun N-Terminal Kinase (JNK) 2 and 3 Inhibitors with In Vitro CNS-like Pharmacokinetic Properties

PDB Details

PDB ID
3OY1
Status
CURRENT
Deposition Date
2010-09-22
Modification Date
2011-08-17
Pubmed ID
21112785
Method
X-RAY DIFFRACTION
Resolution (Å)
1.7
UniProt Accessions
P53779

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 0 20
A C EDI 1 19
A C DEF 3 13
A C DFG 4 11
A C PDIG 7 2
A N PIF 0 18
A N ATP 1 16
A N DFG 4 8
A N ATP 11 2

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Legend

Color Name Hit Count