Crystal Structure of Human B-Raf Kinase Domain in Complex with a Non-Oxime Furopyridine Inhibitor

PDB Details

PDB ID
3PRF
Status
CURRENT
Deposition Date
2010-11-29
Modification Date
2011-03-02
Pubmed ID
21251822
Method
X-RAY DIFFRACTION
Resolution (Å)
2.9
UniProt Accessions
P15056

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C AAS 2 14
A N ATP 1 15
A N MPP 2 14
A N ATP 3 12
A N MPP 4 11
A N ATP 5 9
A N ATP 7 4
A N DFG 8 4
A N MPP 9 2
B N ATP 1 16
B N ATP 2 14
B N MPP 3 14
B N DFG 4 13
B N ATP 5 7
B N MPP 6 7
B N DFG 8 2

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Legend

Color Name Hit Count