Crystal Structure of Human B-Raf Kinase in Complex with a Non-Oxime Furopyridine Inhibitor

PDB Details

PDB ID
3PRI
Status
CURRENT
Deposition Date
2010-11-29
Modification Date
2011-03-02
Pubmed ID
21251822
Method
X-RAY DIFFRACTION
Resolution (Å)
3.5
UniProt Accessions
P15056

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C AAS 4 10
A N ATP 0 17
A N ATP 2 15
A N MPP 3 13
A N MPP 5 7
A N DFG 7 3
A N DFG 9 2
B C AAS 5 9
B C AAS 8 5
B N ATP 1 15
B N MPP 2 14
B N ATP 3 10
B N MPP 4 9
B N ATP 7 7
B N DFG 8 6
B N ATP 9 1

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Legend

Color Name Hit Count