Furo[2,3-c]pyridine-based Indanone Oximes as Potent and Selective B-Raf Inhibitors

PDB Details

PDB ID
3PSB
Status
CURRENT
Deposition Date
2010-12-01
Modification Date
2011-02-23
Pubmed ID
21211972
Method
X-RAY DIFFRACTION
Resolution (Å)
3.4
UniProt Accessions
P15056

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A N MT3 0 18
A N MPP 1 15
A N ATP 2 14
A N ATP 3 12
A N MPP 7 6
B C EDI 3 14
B N MPP 1 16
B N MT3 2 14
B N ATP 3 13
B N ATP 4 12
B N MPP 5 9
B N DFG 7 2

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Legend

Color Name Hit Count