Non-oxime pyrazole based inhibitors of B-Raf kinase

PDB Details

PDB ID
3PSD
Status
CURRENT
Deposition Date
2010-12-01
Modification Date
2011-06-01
Pubmed ID
21536432
Method
X-RAY DIFFRACTION
Resolution (Å)
3.6
UniProt Accessions
P15056

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 5 7
A N MT3 0 20
A N MPP 1 17
A N MPP 3 13
A N ATP 4 12
A N DFG 7 3
A N MPP 8 2
A N DFG 9 2
B N MPP 0 16
B N ATP 1 15
B N ATP 2 14
B N MT3 4 9
B N MPP 5 9
B N MT3 7 5
B N DFG 8 4
B N DFG 10 2

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Legend

Color Name Hit Count