Crystal structure of the ACVR1 kinase domain in complex with LDN-193189

PDB Details

PDB ID
3Q4U
Status
CURRENT
Deposition Date
2010-12-24
Modification Date
2014-06-18
Pubmed ID
23646137
Method
X-RAY DIFFRACTION
Resolution (Å)
1.82
UniProt Accessions
Q04771

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 0 15
A C AAS 1 14
A C AAS 9 3
A N ATP 0 26
A N DFG 1 17
A N ATP 7 4
B C EDI 0 17
B C AAS 7 4
B N DFG 0 21
B N ATP 1 17
B N PIF 3 9
B N ATP 5 8
B N MT3 10 2
C C AAS 0 16
C C EDI 6 5
C N ATP 0 22
C N DFG 1 20
C N ATP 3 13
D C AAS 0 16
D C EDI 4 10
D C AAS 6 8
D N ATP 0 18
D N MPP 1 16
D N DFG 2 16
D N ATP 4 11
D N DFG 9 1

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Legend

Color Name Hit Count