Design and synthesis of brain penetrant selective JNK inhibitors with improved pharmacokinetic properties for the prevention of neurodegeneration

PDB Details

PDB ID
3RTP
Status
CURRENT
Deposition Date
2011-05-03
Modification Date
2013-05-08
Pubmed ID
21813278
Method
X-RAY DIFFRACTION
Resolution (Å)
2.4
UniProt Accessions
P53779

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DEF 0 16
A C EDI 1 15
A C EDI 3 11
A C DFG 6 7
A C DRS 9 4
A C PDIG 10 2
A N ATP 0 19
A N PIF 1 17
A N PIF 2 17

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Legend

Color Name Hit Count