Crystal structure of spleen tyrosine kinase (SYK) in complex with a diaminopyrimidine carboxamide inhibitor

PDB Details

PDB ID
3SRV
Status
CURRENT
Deposition Date
2011-07-07
Modification Date
2011-10-12
Pubmed ID
21903390
Method
X-RAY DIFFRACTION
Resolution (Å)
1.95
UniProt Accessions
P43405

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 6 6
A N DFG 3 13
A N MPP 5 8
A N ATP 6 7
B C EDI 5 6
B C PDIG 7 3
B N MPP 1 19
B N ATP 2 16
B N DFG 4 7
B N DFG 6 2

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Legend

Color Name Hit Count