Co-structure of Fibroblast Growth Factor Receptor 1 kinase domain with 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (BGJ398)

PDB Details

PDB ID
3TT0
Status
CURRENT
Deposition Date
2011-09-13
Modification Date
2012-06-13
Pubmed ID
21936542
Method
X-RAY DIFFRACTION
Resolution (Å)
2.8
UniProt Accessions
P11362

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C AAS 3 11
A N ATP 0 19
A N MPP 1 17
A N DFG 3 9
A N MPP 4 8
A N ATP 7 4
B C EDI 3 16
B C CMP 6 7
B C AAS 9 2
B N MT3 0 18
B N MPP 6 7
B N ATP 7 7
B N DFG 8 3

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Legend

Color Name Hit Count