Crystal Structure of JNK3 complexed with CC-930, an orally active anti-fibrotic JNK inhibitor

PDB Details

PDB ID
3TTI
Status
CURRENT
Deposition Date
2011-09-14
Modification Date
2012-02-08
Pubmed ID
22244937
Method
X-RAY DIFFRACTION
Resolution (Å)
2.2
UniProt Accessions
P53779

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 0 24
A C PDIG 1 15
A C DEF 2 14
A C DFG 4 11
A C DRS 6 4
A C PDIG 7 1
A N PIF 0 17
A N ATP 1 17
A N ATP 2 15
A N DFG 4 9

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Legend

Color Name Hit Count