Crystal structure of SYK kinase domain with 1-(5-(6,7-dimethoxyquinolin-4-yloxy)pyridin-2-yl)-3-((1R,2S)-2-phenylcyclopropyl)urea

PDB Details

PDB ID
3TUB
Status
CURRENT
Deposition Date
2011-09-16
Modification Date
2012-10-17
Pubmed ID
22759374
Method
X-RAY DIFFRACTION
Resolution (Å)
2.23
UniProt Accessions
P43405

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DFG 1 15
A C PDIG 6 3
A N DFG 2 17
A N MPP 4 7
A N ATP 5 6
A N MPP 10 2

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Legend

Color Name Hit Count