Crystal Structure of Interleukin-2 Inducible T-cell Kinase Itk Catalytic Domain with Thienopyrazolylindole Inhibitor 542

PDB Details

PDB ID
3V5L
Status
CURRENT
Deposition Date
2011-12-16
Modification Date
2012-05-02
Pubmed ID
22464456
Method
X-RAY DIFFRACTION
Resolution (Å)
1.86
UniProt Accessions
Q08881

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C AAS 1 17
A C DRS 3 11
A N ATP 3 15
A N MPP 5 5
B C PDIG 2 16
B C DRS 3 16
B C AAS 5 7
B C CMP 8 4
B N ATP 1 16
B N ATP 2 14
C C AAS 2 12
C C DRS 3 12
C N ATP 2 14
C N ATP 3 14
C N PIF 4 10
C N MT3 6 3
D C AAS 0 19
D C DRS 3 9
D N PIF 1 12
D N ATP 2 12
D N ATP 4 10
D N MT3 7 3
D N ATP 9 2

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Legend

Color Name Hit Count