Discovery of a selective TRK Inhibitor with efficacy in rodent cancer tumor models

PDB Details

PDB ID
3V5Q
Status
CURRENT
Deposition Date
2011-12-16
Modification Date
2012-02-08
Method
X-RAY DIFFRACTION
Resolution (Å)
2.2
UniProt Accessions
Q16288

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 0 17
A C DFG 3 11
A N ATP 1 16
A N MT3 2 12
A N MPP 5 8
A N PIF 6 7
A N MPP 7 6
A N ATP 8 5
A N MT3 9 2
B C EDI 5 10
B C DFG 6 8
B N ATP 2 15
B N MPP 4 8
B N MT3 5 8
B N ATP 7 4
B N PIF 8 4

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Legend

Color Name Hit Count