Crystal Structure of Interleukin-2 Inducible T-cell Kinase Itk Catalytic Domain with Thienopyrazolylindole Inhibitor 469

PDB Details

PDB ID
3V8W
Status
CURRENT
Deposition Date
2011-12-23
Modification Date
2012-05-02
Pubmed ID
22464456
Method
X-RAY DIFFRACTION
Resolution (Å)
2.27
UniProt Accessions
Q08881

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DRS 2 11
A C AAS 8 5
A N ATP 1 15
A N MT3 3 13
A N ATP 5 11
A N PIF 6 4
B C AAS 0 17
B C DRS 2 14
B C PDIG 6 7
B N ATP 2 12
B N MT3 4 11
B N ATP 6 9

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Legend

Color Name Hit Count