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Crystal structure of HCK complexed with a pyrazolo-pyrimidine inhibitor tert-butyl {4-[4-amino-1-(propan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-2-methoxyphenyl}carbamate
PDB Details
PDB ID
3VS6
Status
CURRENT
Deposition Date
2012-04-21
Modification Date
2013-05-01
Pubmed ID
23596204
Method
X-RAY DIFFRACTION
Resolution (Å)
2.37
UniProt Accessions
P08631
Mapping Results
Chain
Terminus
Site
Consensus Site Rank
Consensus Site Population
A
C
PDIG
7
5
A
N
MPP
1
16
A
N
ATP
2
16
A
N
ATP
3
12
A
N
MT3
4
10
A
N
ATP
6
7
A
N
MT3
7
5
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Chain: A
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Name
Hit Count
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Chain: A