Crystal structure of human apoptosis signal-regulating kinase 1 (ASK1) with imidazopyridine inhibitor

PDB Details

PDB ID
3VW6
Status
CURRENT
Deposition Date
2012-08-06
Modification Date
2012-10-31
Method
X-RAY DIFFRACTION
Resolution (Å)
2.4
UniProt Accessions
Q99683

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DRS 2 15
A C DEF 3 14
A C EDI 5 7
A N DFG 0 15
A N ATP 2 13
A N MPP 3 12
A N MPP 4 10
A N ATP 5 8
A N MPP 7 2
B C PDIG 1 12
B C DRS 3 12
B N DFG 0 20
B N ATP 1 17
B N MPP 2 12
B N MT3 4 7
B N ATP 5 5
B N ATP 6 3
B N MPP 9 2

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Legend

Color Name Hit Count