CRYSTAL STRUCTURE OF HUMAN MPS1 CATALYTIC DOMAIN IN COMPLEX WITH (E)-3-(4-((6-(((3s,5s,7s)-adamantan-1-yl)amino)-4-amino-5-cyanopyridin-2-yl)amino)-2-(cyanomethoxy)phenyl)-N-(2-methoxyethyl)acrylamide

PDB Details

PDB ID
3WYY
Status
CURRENT
Deposition Date
2014-09-10
Modification Date
2015-04-08
Pubmed ID
25801152
Method
X-RAY DIFFRACTION
Resolution (Å)
3.05
UniProt Accessions
P33981

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 0 20
A C AAS 2 14
A C ATP 4 9
A C PDIG 6 6
A C CMP 7 5
A C AAS 8 3
A N ATP 0 19
A N MPP 2 15
A N MT3 5 9
A N DFG 7 3

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Legend

Color Name Hit Count