CRYSTAL STRUCTURE OF HUMAN MPS1 CATALYTIC DOMAIN IN COMPLEX WITH 4-(6-(cyclohexylamino)-8-(((tetrahydro-2H-pyran-4-yl)methyl)amino)imidazo[1,2-b]pyridazin-3-yl)-N-cyclopropylbenzamide

PDB Details

PDB ID
3WZJ
Status
CURRENT
Deposition Date
2014-09-29
Modification Date
2015-02-11
Pubmed ID
25625617
Method
X-RAY DIFFRACTION
Resolution (Å)
2.75
UniProt Accessions
P33981

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 0 20
A C CMP 1 17
A C ATP 6 6
A C EDI 9 2
A C PDIG 11 1
A N ATP 0 20
A N MT3 1 17
A N MT3 6 5

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Legend

Color Name Hit Count