Aurora kinase selective inhibitors identified using a Taxol-induced checkpoint sensitivity screen.

PDB Details

PDB ID
3ZTX
Status
CURRENT
Deposition Date
2011-07-12
Modification Date
2012-02-01
Pubmed ID
21992004
Method
X-RAY DIFFRACTION
Resolution (Å)
1.95
UniProt Accessions
Q6DE08

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 0 23
A C AAS 5 8
A C EDI 6 8
A C CMP 7 5
A N ATP 1 18
A N PIF 3 13
A N PIF 4 10
A N MPP 5 9
A N MT3 6 6
B C EDI 2 13
B C AAS 3 11
B C PDIG 4 11
B C PDIG 6 7
B N ATP 0 16
B N PIF 3 13
B N PIF 4 12
B N MPP 5 10

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Legend

Color Name Hit Count