Structure-based design of orally bioavailable pyrrolopyridine inhibitors of the mitotic kinase MPS1

PDB Details

PDB ID
4C4G
Status
CURRENT
Deposition Date
2013-09-05
Modification Date
2014-01-15
Pubmed ID
24256217
Method
X-RAY DIFFRACTION
Resolution (Å)
2.65
UniProt Accessions
P33981

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 1 16
A C EDI 5 7
A C PDIG 8 3
A N ATP 0 17
A N MT3 4 9
A N DFG 5 9
A N MPP 7 7
A N MT3 8 2

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Legend

Color Name Hit Count