Structure of the kinase domain of human RIPK2 in complex with ponatinib

PDB Details

PDB ID
4C8B
Status
CURRENT
Deposition Date
2013-09-30
Modification Date
2013-10-16
Method
X-RAY DIFFRACTION
Resolution (Å)
2.75
UniProt Accessions
O43353

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DRS 2 14
A C CMP 5 9
A C DRS 7 6
A N ATP 0 27
A N MPP 3 8
A N MT3 5 6
A N MPP 6 5
B C AAS 2 14
B C DRS 5 6
B C CMP 6 6
B C DRS 7 6
B N ATP 0 16
B N ATP 2 15
B N MT3 5 7
B N MPP 7 5
B N MPP 8 3

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Legend

Color Name Hit Count