Crystal Structure of the Kinase domain of Human B-raf with a [1,3]thiazolo[5,4-b]pyridine derivative

PDB Details

PDB ID
4DBN
Status
CURRENT
Deposition Date
2012-01-16
Modification Date
2012-06-13
Pubmed ID
22376051
Method
X-RAY DIFFRACTION
Resolution (Å)
3.15
UniProt Accessions
P15056

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 1 20
A C DFG 4 9
A N ATP 2 15
A N MPP 4 14
A N ATP 5 8
A N MPP 7 2
B C EDI 2 15
B C DFG 5 7
B N MPP 2 14
B N ATP 3 13
B N MT3 5 12
B N ATP 6 10
B N MPP 7 3

Mapping Results Viewer

Use your mouse to drag, rotate, and zoom. Select structure to view on the right using dropdown.
Powered by NGL

Legend

Color Name Hit Count