Crystal structure of the ACVR1 kinase domain in complex with the imidazo[1,2-b]pyridazine inhibitor K00135

PDB Details

PDB ID
4DYM
Status
CURRENT
Deposition Date
2012-02-29
Modification Date
2012-03-21
Method
X-RAY DIFFRACTION
Resolution (Å)
2.42
UniProt Accessions
Q04771

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 0 16
A C AAS 1 14
A C AAS 7 7
A N ATP 0 28
A N DFG 1 18
A N MPP 2 16
A N ATP 6 4

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Legend

Color Name Hit Count