Crystal structure of human CDK8/CYCC in complex with compound 7 (1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]urea)

PDB Details

PDB ID
4F6S
Status
CURRENT
Deposition Date
2012-05-15
Modification Date
2015-04-01
Pubmed ID
23630251
Method
X-RAY DIFFRACTION
Resolution (Å)
2.6
UniProt Accessions
P49336

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 2 12
A C EDI 3 10
A C AAS 4 10
A C AAS 6 8
A C PDIG 7 4
A N MT3 1 16
A N ATP 2 14
A N MT3 3 12
A N MPP 4 8
A N ATP 5 6

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Legend

Color Name Hit Count