Crystal structure of human CDK8/CYCC in complex with compound 5 (1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-[3-(morpholin-4-yl)propyl]urea)

PDB Details

PDB ID
4F6U
Status
CURRENT
Deposition Date
2012-05-15
Modification Date
2015-04-01
Pubmed ID
23630251
Method
X-RAY DIFFRACTION
Resolution (Å)
2.1
UniProt Accessions
P49336

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C AAS 0 16
A C PDIG 1 16
A C EDI 3 12
A C EDI 4 11
A C PDIG 5 9
A C DRS 7 3
A N MPP 0 15
A N ATP 2 12
A N MT3 4 9
A N MT3 6 7
A N ATP 9 2

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Legend

Color Name Hit Count