Crystal structure of human CDK8/CYCC in complex with compound 1 (N-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-4-[2-({[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]carbamoyl}amino)ethyl]piperazine-1-carboxamide)

PDB Details

PDB ID
4F6W
Status
CURRENT
Deposition Date
2012-05-15
Modification Date
2015-04-01
Pubmed ID
23630251
Method
X-RAY DIFFRACTION
Resolution (Å)
2.39
UniProt Accessions
P49336

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 1 16
A C AAS 2 15
A C PDIG 3 13
A C AAS 6 8
A N MT3 0 27
A N ATP 2 9
A N MPP 3 9

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Legend

Color Name Hit Count