Crystal structure of human CDK8/CYCC in complex with compound 3 (1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-(2-hydroxyethyl)urea)

PDB Details

PDB ID
4F7J
Status
CURRENT
Deposition Date
2012-05-16
Modification Date
2015-04-01
Pubmed ID
23630251
Method
X-RAY DIFFRACTION
Resolution (Å)
2.6
UniProt Accessions
P49336

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 0 23
A C AAS 1 14
A C EDI 2 10
A C EDI 6 6
A C EDI 8 5
A C LBP 10 3
A N ATP 0 19
A N MPP 4 8
A N ATP 5 6
A N MT3 7 3
A N MT3 10 2
A N DFG 12 2

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Legend

Color Name Hit Count