Crystal structure of human CDK8/CYCC in complex with compound 2 (tert-butyl [3-({[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]carbamoyl}amino)propyl]carbamate)

PDB Details

PDB ID
4F7L
Status
CURRENT
Deposition Date
2012-05-16
Modification Date
2015-04-01
Pubmed ID
23630251
Method
X-RAY DIFFRACTION
Resolution (Å)
2.9
UniProt Accessions
P49336

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 0 21
A C EDI 1 16
A C EDI 3 8
A C EDI 4 8
A C DRS 6 5
A C LBP 9 4
A C AAS 10 3
A C LBP 11 3
A C AAS 12 2
A N MT3 0 22
A N MPP 1 17
A N ATP 5 6
A N MT3 6 6
A N MT3 9 2

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Legend

Color Name Hit Count