Crystal structure of human CDK8/CYCC in complex with compound 11 (1-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-3-(5-hydroxypentyl)urea)

PDB Details

PDB ID
4F7N
Status
CURRENT
Deposition Date
2012-05-16
Modification Date
2015-04-01
Pubmed ID
23630251
Method
X-RAY DIFFRACTION
Resolution (Å)
2.65
UniProt Accessions
P49336

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C PDIG 0 23
A C AAS 1 16
A C EDI 3 12
A C EDI 4 10
A C LBP 7 2
A N ATP 1 18
A N MPP 2 11
A N MT3 5 8
A N ATP 7 4
A N MT3 8 3

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Legend

Color Name Hit Count