Crystal structure of EGFR kinase T790M in complex with BIBW2992

PDB Details

PDB ID
4G5P
Status
CURRENT
Deposition Date
2012-07-18
Modification Date
2012-10-31
Pubmed ID
22888144
Method
X-RAY DIFFRACTION
Resolution (Å)
3.17
UniProt Accessions
P00533

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C DRS 2 14
A C EDI 5 5
A N MT3 0 20
A N DFG 3 12
A N ATP 10 2
B C ATP 2 13
B C EDI 4 11
B C LBP 7 4
B C PDIG 8 2
B N MT3 0 16
B N DFG 1 16
B N ATP 4 11

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Legend

Color Name Hit Count