B-Raf V600E Kinase Domain Bound to a Type II Dihydroquinazoline Inhibitor

PDB Details

PDB ID
4G9R
Status
CURRENT
Deposition Date
2012-07-24
Modification Date
2012-11-14
Pubmed ID
22954737
Method
X-RAY DIFFRACTION
Resolution (Å)
3.2
UniProt Accessions
P15056

Mapping Results

Chain Terminus Site Consensus Site Rank Consensus Site Population
A C EDI 3 12
A C DFG 8 4
A C DFG 9 3
A N ATP 0 16
A N MPP 2 14
A N MT3 4 10
A N ATP 5 9
A N MPP 8 4
B C DFG 3 14
B C AAS 6 5
B N ATP 0 23
B N MT3 1 18
B N MPP 2 16
B N MPP 3 10
B N MT3 6 4

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Legend

Color Name Hit Count